Inhibit Cellular Senescence
Cellular senescence is a natural part of the aging process where tired cells no longer function optimally. It can affect organ function, cellular metabolism, inflammation response, and more. To combat this phenomenon, Life Extension® has partnered with Insilico Medicine, Inc. to bring you Ageless Cell™, the first supplement in our breakthrough GEROPROTECT™ line. Senior citizens rejoice because now there’s an anti-aging solution!
As we age, our natural ability to expel these cells from our vital systems declines. The accumulation of these senescent and pre-senescent cells plays a major part in biological aging. Ageless Cell™ delivers unique ingredients that help inhibit cellular senescence.
A cutting-edge computer simulation has revealed key nutrients that promote youthful function throughout the body. Developed with the power of AI (Artificial Intelligence). Read more about this in Forbes Magazine.
Ageless Cell™ provides a nutrient cocktail that functions as a geroprotector (a compound with the ability to target and favorably impact known longevity and/or anti-aging pathways).
This scientific collaboration, via a meta-analysis of thousands of published studies and an
in vitro in vivo in silico** study, resulted in the identification of four age-modulating nutrients:
- N-acetyl-cysteine (NAC)
- epigallocatecin-gallate (EGCG)
- gamma tocotrienol
First-ever Geroprotective Formulation Based on Artificial Intelligence
*Artificial intelligence is the development and utilization of computer systems that are able to perform tasks that normally require human intelligence. In the case of this product, artificial intelligence was used to estimate the impact of various nutrients on human lifespan using a complex, proprietary platform. This is beneficial because there are limitations to the extrapolation of animal lifespan research to human lifespan research.
** Unlike studies done in the glass dishes of a laboratory (in vitro studies), or those done in living animals (in vivo studies), research done inside a computer exists purely in virtual form, in the silicon chips of the processor, and is referred to as an “in silico” study.
Turn Back the Clock Right at Your Cells
Life Extension then combined these unique ingredients into a single innovative formula. By rejuvenating near- senescent cells and encouraging the body’s healthy process for dealing with senescent cells, Ageless Cell™ helps turn back the clock at the cellular level.
- A natural sulfur-containing molecule that is the precursor to glutathione, which is known for its free radical scavenging capabilities.
- NAC up-regulates signaling pathways that target ROS accumulation to help defend becoming senescent cells from becoming senescent.
Green tea extract (epigallocatecin-gallate (EGCG))
- EGCG is the polyphenol from green tea known for its free radical scavenging and inflammation easing properties.
- Regulates the Wnt signaling pathway, which plays a role in determining the proper fate of developing cells.
- Attenuates senescence-associated oxidative stress inflammation and inflammation.
- Naturally occurring polyphenolic flavonoid that is found in berries, fruits, vegetables, herbs, tea and wine.
- Regulates the p38 MAPK signaling pathway that is involved healthy aging in many tissues.
Gamma Tocotrienol and Tocopherol Vitamin E
- One of the eight forms of vitamin E that promotes youthful cellular health by modulating the expression of senescence-associated genes (eg, IL-6 genes).
- Supports bone health by modulating the mevalonate metabolic pathway osteoblast formation in favor of osteoblast formation.
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These statements have not been evaluated by the FDA. They are not intended to treat, diagnose, cure or prevent any disease.